Titre du document

Blind randomized controlled study of the efficacy of cognitive training in Parkinson's disease

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Ortho

Auteur(s)
  • Anna Prats París MS, PhDc 1,2
  • Heidi Guerra Saleta PhDc 3
  • Maria de la Cruz Crespo Maraver PhDc 1,4
  • Emmanuel Silvestre PhD 5
  • Maite Garolera Freixa PhD 6
  • Cristina Petit Torrellas BA 1
  • Silvia Alonso Pont BA 1
  • Marc Fabra Nadal MS 1
  • Sheila Alcaine Garcia BA 1
  • Maria Victoria Perea Bartolomé MD 3
  • Valentina Ladera Fernández PhD 3
  • Àngels Rusiñol Bayés MD, PhD 1,7
Affiliation(s)
  • Unitat de Parkinson i Trastorns del Moviment, Centro Médico Teknon. Barcelona, Spain
  • Universidad Autònoma de Barcelona, Dpto. Biología Celular, Fisiología e Inmunología, Instituto de Neurociencias (INc), Barcelona, Spain
  • Universidad de Salamanca, Facultad de Psicología, Dpto. Psicología Básica, Psicobiología y Metodología. Salamanca, Spain
  • Divisió de Salut Mental, Fundació Althaia, Manresa, Spain
  • Silvestre Hispanic Market Research & Services, Rocky Hill, Connecticut, USA
  • Consorci Sanitari de Terrasa Hospital, Terrasa, Spain
  • Correspondence address: Unidad de Parkinson y Trastornos del Movimiento, Centro Médico Teknon, Pso. Bonanova 26, Barcelona, Spain. 08022
Langue(s) du document
Anglais
Revue

Movement Disorders

Éditeur
Wiley
Année de publication
2011
Type de publication
Journal
Type de document
Article
Résumé

The aim of this study was to analyze the efficacy of a cognitive training program on cognitive performance and quality of life in nondemented Parkinson's disease patients. Participants who met UK Brain Bank diagnosis criteria for Parkinson's disease, with I–III Hoehn & Yahr, aged 50–80, and nondemented (Mini‐Mental State Examination ≥ 23) were recruited. Patient's cognitive performance and functional and quality‐of‐life measures were assessed with standardized neuropsychological tests and scales at baseline and after 4 weeks. Subjects were randomly and blindly allocated by age and premorbid intelligence (Vocabulary, Wechsler Adult Intelligence Scale‐III) into 2 groups: an experimental group and a control group. The experimental group received 4 weeks of 3 weekly 45‐minute sessions using multimedia software and paper‐and‐pencil cognitive exercises, and the control group received speech therapy. A total of 28 patients were analyzed. Compared with the control group participants (n = 12), the experimental group participants (n = 16) demonstrated improved performance in tests of attention, information processing speed, memory, visuospatial and visuoconstructive abilities, semantic verbal fluency, and executive functions. There were no observable benefits in self‐reported quality of life or cognitive difficulties in activities of daily living. We concluded that intensive cognitive training may be a useful tool in the management of cognitive functions in Parkinson's disease. © 2011 Movement Disorder Society

Mots-clés d'auteur
  • Parkinson's disease
  • cognition
  • cognitive training neuropsychology
  • cognitive impairment
Catégories WoS
  • 1 - science ; 2 - clinical neurology
Catégories Science-Metrix
  • 1 - health sciences ; 2 - clinical medicine ; 3 - neurology & neurosurgery
Catégories Scopus
  • 1 - Health Sciences ; 2 - Medicine ; 3 - Clinical Neurology
  • 1 - Life Sciences ; 2 - Neuroscience ; 3 - Neurology
Catégories INIST
  • 1 - sciences humaines et sociales
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9.138
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